Research

Estimation of Peak Expiratory Flow (PEF)

 2016.12.7.

Proxysmal dyspnea is the chief complicant in patients with bronchial asthma and the tenet of bronchial asthma is amleriorating this syndrome.

It is a crucial problem to diagnose asthma early and correctly and to prevent.

The measurement of Peak Expiratory Flow is a simple and objectivemethod by which we can evauate the reversible change of respiratory tract.

To detect the severity of bronchial asthma and the effect of treatment it is necessary to measure PEF in normal condition.

A study of measuring the range of PEF in 673 normal adults (male: 434, female: 239) aged 17 to 76 identified the estimation of PEF in bronchial asthma in the department of medical infomatics.

PEF is measured by Peak flow meter. The steps of measurement are as follows.

Ⅰ.The most inspiration with a peak flow meter in their mouths in the standing and sedentary position.

Ⅱ. Strong and quick expiration within 1 second.

We chose the largest value of 3 values.

The regression analysis is applied and an objective variate is PEF, factorial variates are age and height.

We detected the estimation in male and femal gender respectively.

Male gender.

PEF(male) = exp(6.912 + 0.411 * lnx1 - 0.013 * x1 - 274.275 * 1 / x2)

x1: Age, x2: Height

Femal gender

PEF(female) = exp(5.444 + 0.304 * lnx1 - 0.016 * x1 + 0.153 * 1 / x2)

x1: Age, x2: Height

In case of male gender the maximum of error is 14.3%, the average of error is 2.7% and in case of female gender the maximum is 2.7%, the average is 2.4%.

By using the regression equation, severity or effect of the treatment of astma can be evaluated efficiently.

A collective study with clinical institutes will be continued to improve the correctness of the estimation and to solve problems in clinical practice of respiratory disease.